I don't know about the 6.0L tuning, but I have the XRT Pro on my 6.4L and you can switch power on the fly and custom tune the trans.
But I guess you can't assume they do it for all models...
you can't shift H&S tunes on the fly with the XRT? just mini maxx and black maxx. and can't shift KEM on the fly ever.
but it's a totally dif game on the 6.0s
Well they do tune the trans it just wont allow for sotf when cuatom tunes are on it