Harness usually grounds out and blows a fuse in the BJB causing a crank and no start condition. Can also cause a lack or loss of power.
TSB 07-23-2.
P0088 was an ongoing issue with earlier trucks, the original fix was replacement of the HPFP. Now the repair is just a reflash. All they did was widen the failure parameter a little.
Make sure the truck is at the latest calibration level, and ensure proper base fuel pressure and delivery.