Maybe ! What year is your truck ? I would check for loose or missing turbo bolts. 04.5-05 6.0s have more of a problem with it because of the pedestal design. When Ford switch the location of the rear bolt from horizontal to vertical it weakened to pedestal design. Here is a pic of an 04.5 on the left and a 06 on the right.
05.5-07 where still covered in the TSB I believe, just bc resonance could still happen even in the later pedestal. Ford sales a updated pedestal. Noise is the only thing to worry about on this.
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