I don't think it has anything to do with lifting it. When you can go right to the dealership and drive a truck right off the lot that does it brand new....LOL. All (6) CCLB trucks my friend drove all did it right at the dealership. His CCLB truck did it too. Installed a lift kit on CCLB and the hop was still there. I know he had to do quite a bit of messing with the shock valving to get rid of the hop.
When you think about how long the entire drive train is on a CCLB truck. From front of motor to the rear axle and all that spinning at X,XXX rpms. It is probably hitting the resonant frequency of the drivetrain. When it does it your truck is bouncing vertically up and down. You could brace the entire bottom of the frame all the way front to back and nomatter what it will still bounce up and down. The only way to make the frame say stronger is by adding material to it from almost one end to the other. And also you would need some heftier shocks front and rear. That is why some of the guys running the larger shocks like 2.5's don't seem to feel any hopping. If you have ****ty shocks on your truck, it probably is going to be worse.
When you start looking across the interweb dodges, f150s and not sure on chevys all have complained about that 45 mph speed and hopping. I don't think they all do it but it seems to be something somewhat common.
Some people see a reduction in hopping when they have weight in the bed. This can affect that resonant frequency and when you add weight in the bed it also changes the pinion angle on the axle.
I don't think this is a two piece driveline versus a 1 piece driveline. I think that may help with the CCSB but not the CCLB. The CCLB seem to be very prone to this. It is hard to get a one piece driveline made that is that long, kind of a safety issue, and people have done it and still seem to have the hop. Not everybody wants to spend 1,500 on a driveline that long either.
I don't think this has anything to do with the hop on take off. That is mainly driveline/pinion alignment issue or not having traction bars or it is something else with your drivetrain.