If youre going to be towing 25k all the time, honestly stick with a stock nozzle. a 100 percent nozzle, no matter how you slice it, will have downsides to towing heavy on a 6.0.
We have built a lot of 6.0s locally for construction guys that tow dump trailers and goosenecks on a regular basis. The setup that works the best is the stock turbo and 190/75s. The trucks still get to the 500 horse range but towing is not to bad with propper tuning and a watchful eye on the pyro. a 100 percent nozzle is always going to haze, and it does not matter what someone tells you can or cant be done in the tuning. The only way to get around this would be a STELLAR set of twins utilizing a very responsive vgt.