You guys got me thinking on this. I'm just not smart or brave enough to test this out due to my lack of tuning skills.
After reading a little more, the dmax and cummins guys who removed pilot injection advanced the timing slightly to clear the white haze. Sounds like they just shut it off all together, tested the tune, noted where it hazed thed bumped the timing up slightly till it cleared. Google "remove pilot injection" and numerous posts will come up with some pretty good info.
As for pressure spikes, without pilot injection it's probably very similar to what a 6.0 would have, maybe slightly greater since the timing will be off until that gets tweaked too. The spike in pressure is actually what give a diesel it's knock, cackle or whatever you want to call it. I am by no means a diesel tuner just been reading up a little to share some insight.